Tdp43 Depletion Rescues Aberrant Cftr Exon 9 Skipping
New research highlights that Tdp43 depletion successfully rescues aberrant Cftr exon 9 skipping. This discovery is crucial for understanding molecular mechanisms in diseases like cystic fibrosis, where Cftr gene mutations and splicing errors are central. Modulating Tdp43 levels could offer novel therapeutic insights into correcting Cftr RNA processing defects.