Epigenetic Alterations In Oncogenesis
Epigenetic alterations represent modifications to gene expression that do not involve changes to the underlying DNA sequence, yet play a critical role in oncogenesis. These include processes like DNA methylation and histone modifications, which can inappropriately activate or silence genes, driving the initiation and progression of cancer development. Understanding these epigenetic changes is vital for developing new diagnostic and therapeutic strategies against cancer, as they offer reversible targets for intervention in gene regulation cancer pathways.