Dataset Browser

Explore the advanced capabilities of three-dimensional electron microscopy for visualizing macromolecular assemblies. This powerful technique provides high-resolution insights into complex biological molecules, crucial for understanding their structure, function, and interactions within cellular environments.

Explore how Small Angle X-ray Scattering (SAXS) and Small Angle Neutron Scattering (SANS) are employed to analyze biomacromolecular solutions. These powerful techniques provide critical insights into the structure, size, and interactions of proteins, nucleic acids, and other biological macromolecules, advancing our understanding of their function and behavior in solution states.

Isotope labeling is a crucial technique in biomolecular NMR spectroscopy, significantly enhancing the clarity and interpretability of data for the structural and dynamic analysis of macromolecules. By selectively incorporating specific isotopes like 13C and 15N, researchers can overcome spectral crowding, improve signal resolution, and facilitate the assignment of resonances, which is essential for determining protein structures, understanding ligand binding, and studying complex biomolecular interactions with high precision.

Explore the latest advances in structural biology, unraveling the complex architectures of biomolecules with groundbreaking techniques. These developments are revolutionizing our understanding of cellular processes, paving the way for significant progress in drug discovery, disease mechanisms, and the design of novel therapeutics.

Understanding the structural basis of biological energy generation is crucial for deciphering the intricate molecular mechanisms that underpin life. This involves studying the three-dimensional arrangements of proteins and other biomolecules involved in processes like cellular respiration and photosynthesis, providing insights into how energy is efficiently extracted, converted, and utilized within living organisms. Analyzing these structures at atomic resolution helps us comprehend the catalytic cycles, electron transport chains, and proton gradients that drive ATP synthesis, ultimately powering all cellular activities.